Article
Association of ATM, CDH1 and TP53 genes polymorphisms with familial breast cancer in patients of Khyber Pakhtunkhwa, Pakistan.
African health sciences - 1 Sept 2022
Rahim Abdur, Zakiullah, Jan Asif, Ali Johar, Khuda Fazli, Muhammad Basir, Khan Hamayun, Shah Hussain, Akbar Rani
Abstract excerpt
Background: Genetic studies play a significant role in understanding the underlying risk factors of breast cancer. Polymorphism in the tumor suppressor gene TP 53, CDH1 and ATM genes are found to increase susceptibility for breast cancer globally. Objective: This study aimed to identify/analyze the contribution of genetic polymorphisms in the breast cancer candidate genes ATM, TP53 and CDH1 that may be associated...
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