Article
Mutational and Expressional Deregulation of the CHEK1 Gene in Breast Cancer Patients.
Cancer investigation - 1 Jul 2026
Mehmood Azhar, Mahjabeen Ishrat, Nisar Asif, Umar Muhammad, Kayani Mahmood Akhtar
Abstract excerpt
BACKGROUND: Breast cancer burden is increasing day by day. The identification of novel genetic markers based on polymorphism and expression analysis is necessary to reduce the suffering of patients. AIMS: The current study is divided into two parts; firstly, the possible association of hotspot CHEK1 gene single nucleotide polymorphisms (SNPs) was investigated in breast cancer patients. Secondly, the relative...
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