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Article

Association of common BRCA1 variants with predisposition to breast tumors in Pakistan.

Annals of human genetics - 1 Sept 2023

Siddique Ayesha, Fatima Warda, Shahid Naeem

Abstract excerpt

BRCA1 variants are extensively associated with increased risk of breast cancer. Early detection and screening of variants is still rare in developing countries. Here, we investigated six BRCA1 variants in 300 subjects from Pakistani population using tetra amplification-refractory mutation system (T-ARMS) PCR. Our results indicate significant association of BRCA1 variants rs8176237 (AA; OR 8.2, 95% CI 3.02-22.64,...

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Identifiers

PMID: 37191028
DOI: 10.1111/ahg.12511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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