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Article

Epigenetic Regulation of Corneal Epithelial Differentiation by TET2

2 Feb 2023

Abstract excerpt

Epigenetic DNA modification by 5-hydroxymethylcytosine (5hmC), generated by the Ten-eleven translocation (TET) dioxygenases, regulates diverse biological functions in many organ tissues, including the mammalian eye. For example, 5hmC has been shown to be involved in epigenetic regulation of retinal gene expression. However, a functional role of 5hmC in corneal differentiation has not been investigated to date....

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PMID: 36769164
DOI: 10.3390/ijms24032841

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