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Article

Comprehensive characterization of DNA methylation changes in Fuchs endothelial corneal dystrophy

6 Apr 2017

Abstract excerpt

Transparency of the human cornea is necessary for vision. Fuchs Endothelial Corneal Dystrophy (FECD) is a bilateral, heritable degeneration of the corneal endothelium, and a leading indication for corneal transplantation in developed countries. While the early onset, and rarer, form of FECD has been linked to COL8A2 mutations, the more common, late onset form of FECD has genetic mutations linked to only a...

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PMID: 28384203
DOI: 10.1371/journal.pone.0175112

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