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Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review

23 Dec 2019

Abstract excerpt

Network medicine is a molecular-bioinformatic approach analyzing gene-gene interactions that can perturb the human interactome. This review focuses on epigenetic changes involved in several ocular diseases, such as DNA methylation, histone and nonhistone post-translational modifications, and noncoding RNA regulators. Although changes in aberrant DNA methylation play a major role in the pathogenesis of most ocular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31976085
DOI: 10.1155/2019/2424956

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