Article
The FOXP3-924 A/G Single Nucleotide Polymorphism May Be Associated with Predictive Factors for Human T Lymphotropic Virus 1 Associated Myelopathy.
Viral immunology - 1 Mar 2023
Madureira Max W S, Queiroz Maria Alice F, Lima Sandra S, Pereira Leonn M S, da Costa Carlos A, de Sousa Maísa S, Feitosa Rosimar N M, Monteiro Jacqueline C, Ishak Ricardo, Vallinoto Antonio C R, Rangel da Silva Andréa Nazaré M
Abstract excerpt
Human T lymphotropic virus 1 (HTLV-1) is a retrovirus associated with inflammatory diseases, including HTLV-1-associated myelopathy (HAM), and host genetic factors may be involved in disease evolution. The forkhead Box P3 (FOXP3) transcription factor is linked to homeostasis of the immune system, and the presence of polymorphisms in the promoter region of the FOXP3 gene should reflect its expression levels and...
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