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Article

Forkhead Box P3 (Foxp3) serum level and Foxp3 Gene-Promoter polymorphisms in Egyptian rheumatoid arthritis patients: A case-control study.

The Egyptian journal of immunology - 1 Apr 2021

Ikram Enas M, Allam Ayman A, Meawed Takwa E, Abd El-Wahab Shimaa M, Ramadan Raghdaa A

Abstract excerpt

Regulatory T (Treg) cells are the chief player in induction of autotolerance and the transcription factor, Forkhead Box P3 (Foxp3), is the master regulator of their development and function. Polymorphisms in Foxp3 locus affect Foxp3 expression and can influence Treg cell function. This study aimed to determine the frequency of -3279C/A and -924A/G polymorphisms in the promoter region of the Foxp3 gene in Egyptian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34185454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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