Article
Analysis of chosen polymorphisms in FoxP3 gene in children and adolescents with autoimmune thyroid diseases.
Autoimmunity - 1 Sept 2014
Bossowski Artur, Borysewicz-Sańczyk Hanna, Wawrusiewicz-Kurylonek Natalia, Zasim Aneta, Szalecki Mieczysław, Wikiera Beata, Barg Ewa, Myśliwiec Małgorzata, Kucharska Anna, Bossowska Anna, Gościk Joanna, Ziora Katarzyna, Górska Maria, Krętowski Adam
Abstract excerpt
INTRODUCTION: Forkhead box P3 (Foxp3) is an important regulatory factor for the development and function of T regulatory (Treg) cells. Moreover, it has been established that deficiency of the Foxp3 gene in Treg cells suppresses their regulatory function leading to the development of autoimmune diseases especially autoimmune thyroid diseases. The aim of our study was to estimate the association of three...
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