Article
Association of single-nucleotide polymorphisms in FOXP3 gene with systemic lupus erythematosus susceptibility: a case-control study.
Lupus - 1 Feb 2011
Lin Y-C, Lee J-H, Wu A S-H, Tsai C-Y, Yu H-H, Wang L-C, Yang Y-H, Chiang B-L
Abstract excerpt
Foxp3, encoded by the human FOXP3 gene, is a transcription factor that regulates regulatory T-cell (Treg) development and function. Associations have been reported between FOXP3 gene variants and autoimmune endocrinopathy and non-endocrine autoimmune disease. The aim of this study was to investigate the possible influence of single nucleotide polymorphisms (SNP) in the FOXP3 gene on genetic predisposition to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.