Article
Sex and FOXP3 gene rs2232365 polymorphism may be associated with the clinical and pathological aspects of chronic viral diseases.
BMC immunology - 19 Nov 2020
Pereira Leonn Mendes Soares, da Silva Madureira Max Willy, de Castro Renata Bezerra Hermes, Abreu Isabella Nogueira, da Silva Conde Simone Regina Souza, Demachki Sâmia, de Sousa Maisa Silva, Queiroz Maria Alice Freitas, Rangel da Silva Andrea Nazaré M, Lima Sandra Souza, de Oliveira Guimarães Ishak Marluísa, Ishak Ricardo, Vallinoto Antonio Carlos Rosário
Abstract excerpt
BACKGROUND: The forkhead box protein 3 (FOXP3) transcription factor is one of the main markers of immunological suppression in different pathological profiles, and the presence of polymorphic variants may alter the gene expression of this factor. Despite descriptions of an association between the presence of the rs2232365 polymorphism and chronic diseases, the role of the sex variant in this context has not yet...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.