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Article

Single nucleotide polymorphisms in the FOXP3 gene are associated with increased risk of relapsing-remitting multiple sclerosis.

Human antibodies - 1 Jan 2016

Eftekharian Mohammad Mahdi, Sayad Arezou, Omrani Mir Davood, Ghannad Masoud Sabouri, Noroozi Rezvan, Mazdeh Mehrdokht, Mirfakhraie Reza, Movafagh Abolfazl, Roshanaei Ghodratollah, Azimi Tahereh, Inoko Hidetoshi, Taheri Mohammad

Abstract excerpt

BACKGROUND: Although Multiple Sclerosis (MS) is an autoimmune multifactorial disease with unknown etiology, various genetic and environmental factors are known to contribute to the pathogenesis of the disease. OBJECTIVE: Recent studies have confirmed that the suppressive function of regulatory T cells (T (reg)) is impaired in MS patients and that the FOXP3 gene is a crucial transcription factor in the regulation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27792007
DOI: 10.3233/HAB-160299

Genes

FOXP3

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