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Article

FOXP3 gene polymorphisms increase the risk of systemic lupus erythematosus in a Han Chinese population.

Annals of medicine - 1 Dec 2024

Du Shushu, Zhao Lili, Wu Jiaming, Shi Xiaofei, Liu Rongzeng

Abstract excerpt

BACKGROUND: FOXP3 is a transcription factor that regulates the development and function of Treg, playing an essential role in preventing autoimmune diseases. Variation in FOXP3 can impair the function of Treg cells, thus destroying their inhibitory capacity and leading to autoimmune diseases. This paper investigated whether the three SNPs in the FOXP3 gene (-3279 C/A, -924 A/G and -6054 del/ATT) are associated...

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Identifiers

PMID: 38848045
DOI: 10.1080/07853890.2024.2363937
PMCID: PMC11164044

Genes

FOXP3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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