Article
Type 2 diabetes susceptibility genes on mouse chromosome 11 under high sucrose environment.
BMC genetics - 23 Jul 2020
Kobayashi Misato, Ueda Hironori, Babaya Naru, Itoi-Babaya Michiko, Noso Shinsuke, Fujisawa Tomomi, Horio Fumihiko, Ikegami Hiroshi
Abstract excerpt
BACKGROUND: Both genetic and environmental factors contribute to type 2 diabetes development. We used consomic mice established from an animal type 2 diabetes model to identify susceptibility genes that contribute to type 2 diabetes development under specific environments. We previously established consomic strains (C3H-Chr 11NSY and C3H-Chr 14NSY) that possess diabetogenic Chr 11 or 14 of the...
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