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Single-cell transcriptome analysis reveals immunosuppressive landscape in overweight and obese colorectal cancer

4 Feb 2024

Abstract excerpt

Abstract Background Overweight and obesity are established risk factors for various types of cancers including colorectal cancer (CRC). However the underlying molecular mechanisms remain unclear. An in-depth understanding of the oncologic characteristics of overweight and obese CRC at the single-cell level can provide valuable insights for the development of more effective treatment strategies for CRC. Methods We...

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PMID: 38311726
DOI: 10.1186/s12967-024-04921-5

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