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Article

Association of ESR1 gene polymorphisms with the susceptibility to Hepatitis B virus infection and the clinical outcomes.

Journal of medical virology - 1 Feb 2023

Xie Jiaxin, Ding Yibo, Li Xiaopan, Pu Rui, Liu Wenbin, Li Peng, Yin Jianhua

Abstract excerpt

Estrogen receptor alpha (ESR1) has been implicated in the pathological process of Hepatitis B virus (HBV) infection and is probably an important determinant for gender differences. In this study, a total of 975 subjects including 368 healthy controls, 323 hepatocellular carcinoma (HCC) patients with HBsAg positive, and 284 HBV-infected subjects without HCC were included. Three single nucleotide polymorphisms of...

Topics

Humans
Male
Carcinoma, Hepatocellular
Case-Control Studies
Genetic Predisposition to Disease
Genotype
Hepatitis B
Hepatitis B virus
Hepatitis B, Chronic
Liver Cirrhosis
Liver Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 36661054
DOI: 10.1002/jmv.28510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-36661054-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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