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Article

Association of estrogen receptor alpha polymorphisms with susceptibility to chronic hepatitis B virus infection.

Hepatology (Baltimore, Md.) - 1 Aug 2004

Deng Guohong, Zhou Gangqiao, Zhai Yun, Li Shuqing, Li Xuhong, Li Ya, Zhang Ruifang, Yao Zhijian, Shen Yan, Qiang Boqing, Wang Yuming, He Fuchu

Abstract excerpt

Several studies have demonstrated that estrogen receptor alpha (ESR1) participates in the pathogenesis of persistent hepatitis B virus (HBV) infection. To examine whether polymorphisms at the ESR1 gene locus are associated with persistent HBV infection, we resequenced ESR1 genomic region for single nucleotide polymorphisms (SNPs) in 27 unrelated Chinese. Two haplotype-tagged SNPs (htSNP), T29C and A252966G, were...

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Source

Identifiers

PMID: 15368436
DOI: 10.1002/hep.20318

Genes

ESR1

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