Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Estrogen receptor alpha polymorphisms associated with susceptibility to hepatocellular carcinoma in hepatitis B virus carriers.

Gastroenterology - 1 Jun 2006

Zhai Yun, Zhou Gangqiao, Deng Guohong, Xie Weimin, Dong Xiaojia, Zhang Xiumei, Yu Ling, Yang Hao, Yuan Xiaoyan, Zhang Hongxin, Zhi Lianteng, Yao Zhijian, Shen Yan, Qiang Boqing, He Fuchu

Abstract excerpt

BACKGROUND & AIMS: Overexpression of estrogen receptors (ESRs) is implicated in the development of hepatocellular carcinoma (HCC) in both animal models and humans. We examined whether the ESR1 polymorphisms were related to HCC risk among chronic hepatitis B virus carriers. METHODS: Six ESR1 polymorphisms, which are (TA)n repeat in the promoter, T29C at codon 10 in exon 1, PvuII and XbaI site in intron 1, C136474G...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Confidence Intervals

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Estrogen Receptor alpha

Share to Hepatitis B, Chronic

Share to Hepatitis B virus

Share to Liver Neoplasms

Share to Precancerous Conditions

Share to Probability

Source

Identifiers

PMID: 16762623
DOI: 10.1053/j.gastro.2006.02.030

Genes

ESR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estrogen receptor alpha polymorphisms associated with susceptibility to hepatocellular carcinoma in hepatitis B virus carriers.PMID 16762623Read ↗

Association of estrogen receptor alpha polymorphisms with susceptibility to chronic hepatitis B virus infection.Semantic proximity Read ↗

Estrogen receptor alpha gene polymorphisms and risk of HBV-related acute liver failure in the Chinese population.Semantic proximity Read ↗

A cis-acting regulatory variation of the estrogen receptor α (ESR1) gene is associated with hepatitis B virus-related liver cirrhosis.Semantic proximity Read ↗

Association of ESR1 gene polymorphisms with the susceptibility to Hepatitis B virus infection and the clinical outcomes.Semantic proximity Read ↗

Association of PvuII and XbaI polymorphisms in estrogen receptor alpha gene with the risk of hepatitis B virus infection in the Guangxi Zhuang population.Semantic proximity Read ↗

Hepatocellular carcinoma and estrogen receptors: Polymorphisms and isoforms relations and implications.Semantic proximity Read ↗

Polymorphism of estrogen receptor alpha (ESR1) is associated with virological response to entecavir (ETV) in nucleoside-naïve adult patients with chronic hepatitis B.Semantic proximity Read ↗

Association of genetic variants in estrogen receptor α with HCV infection susceptibility and viral clearance in a high-risk Chinese population.Semantic proximity Read ↗

Association between estrogen receptor 1 (ESR1) genetic variations and cancer risk: a meta-analysis.Semantic proximity Read ↗

The Influence of ESR2 Gene Polymorphisms on Susceptibility to Hepatitis B Virus-Related Chronic Hepatitis, Liver Cirrhosis, and Hepatocellular Carcinoma.Semantic proximity Read ↗

Sex-specific association of estrogen receptor 2 polymorphisms with hepatitis C virus infection outcomes in a high-risk Chinese Han population.Semantic proximity Read ↗

T29C genotype polymorphism of estrogen receptor alpha is associated with initial response to interferon-alpha therapy in chronic hepatitis B patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.