Article
Sex-specific association of estrogen receptor 2 polymorphisms with hepatitis C virus infection outcomes in a high-risk Chinese Han population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2014
Cai Li, Gao Chunfang, Tang Shaidi, Wang Jiajia, Xue Xingxin, Yue Ming, Deng Xiaozhao, Su Jing, Peng Zhihang, Lu Yan, Zhang Yun, Wang Jie
Abstract excerpt
Hepatitis C virus (HCV) has different clinical and biological characteristics in women versus men, which suggests the potential involvement of estrogen. Estrogen signaling is mediated by the estrogen receptor, and genetic variations in the estrogen receptor gene might affect the pathology of HCV infection. We performed logistic regression analysis to explore the associations between rs1256049, rs4986938 and...
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