Article
Association of PvuII and XbaI polymorphisms in estrogen receptor alpha gene with the risk of hepatitis B virus infection in the Guangxi Zhuang population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2014
Liu Yanqiong, Liu Yan, Huang Xiamei, Sui Jingzhe, Mo Cuiju, Wang Jian, Peng Qiliu, Deng Yan, Huang Li, Li Shan, Qin Xue
Abstract excerpt
BACKGROUND AND OBJECTIVE: Available evidence has suggested that estrogen receptor alpha (ESR1) is implicated in the pathogenic process of hepatitis B infection. Therefore, we evaluated the association of PvuII (rs2234693) and XbaI (rs9340799) in ESR1 and HBV infection in Guangxi Zhuang populations. METHODS: A total of 389 subjects were divided into four groups: 112 patients with chronic hepatitis B (CHB), 65...
Topics
- Adult
- Alleles
- Carcinoma, Hepatocellular
- Case-Control Studies