Article
Genomics and Epigenomics in the Molecular Biology of Melanoma-A Prerequisite for Biomarkers Studies.
International journal of molecular sciences - 31 Dec 2022
Zob Daniela Luminita, Augustin Iolanda, Caba Lavinia, Panzaru Monica-Cristina, Popa Setalia, Popa Alina Delia, Florea Laura, Gorduza Eusebiu Vlad
Abstract excerpt
Melanoma is a common and aggressive tumor originating from melanocytes. The increasing incidence of cutaneous melanoma in recent last decades highlights the need for predictive biomarkers studies. Melanoma development is a complex process, involving the interplay of genetic, epigenetic, and environmental factors. Genetic aberrations include BRAF, NRAS, NF1, MAP2K1/MAP2K2, KIT, GNAQ, GNA11, CDKN2A, TERT mutations,...
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