Article
The genetics of melanoma: recent advances.
Annual review of genomics and human genetics - 1 Jan 2013
Hill Victoria K, Gartner Jared J, Samuels Yardena, Goldstein Alisa M
Abstract excerpt
Cutaneous malignant melanoma results from the interplay of genetic, host, and environmental factors. Genetic factors implicated in melanoma etiology include inherited high-, intermediate-, and low-risk susceptibility genes as well as numerous somatic mutations in melanoma tumors. CDKN2A is the major high-risk melanoma susceptibility gene identified to date. Recent identification of low-risk loci has been...
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