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Molecular Frontiers in Melanoma: Pathogenesis, Diagnosis, and Therapeutic Advances.

International journal of molecular sciences - 4 Mar 2024

Kim Hyun Jee, Kim Yeong Ho

Abstract excerpt

Melanoma, a highly aggressive skin cancer, is characterized by rapid progression and high mortality. Recent advances in molecular pathogenesis have shed light on genetic and epigenetic changes that drive melanoma development. This review provides an overview of these developments, focusing on molecular mechanisms in melanoma genesis. It highlights how mutations, particularly in the BRAF, NRAS, c-KIT, and...

Topics

Humans
Melanoma
Skin Neoplasms
Mutation
Signal Transduction
GTP-Binding Proteins

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 38474231
DOI: 10.3390/ijms25052984
PMCID: PMC10931637

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