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Advances in Melanoma: From Genetic Insights to Therapeutic Innovations

14 Aug 2024

Abstract excerpt

Advances in melanoma research have unveiled critical insights into its genetic and molecular landscape, leading to significant therapeutic innovations. This review explores the intricate interplay between genetic alterations, such as mutations in BRAF, NRAS, and KIT, and melanoma pathogenesis. The MAPK and PI3K/Akt/mTOR signaling pathways are highlighted for their roles in tumor growth and resistance mechanisms....

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PMID: 39200315
DOI: 10.3390/biomedicines12081851

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