Article
Molecular Pathways in Melanomagenesis: What We Learned from Next-Generation Sequencing Approaches.
Current oncology reports - 14 Sept 2018
Palmieri Giuseppe, Colombino Maria, Casula Milena, Manca Antonella, Mandalà Mario, Cossu Antonio
Abstract excerpt
PURPOSE OF REVIEW: Conventional clinico-pathological features in melanoma patients should be integrated with new molecular diagnostic, predictive, and prognostic factors coming from the expanding genomic profiles. Cutaneous melanoma (CM), even differing in biological behavior according to sun-exposure levels on the skin areas where it arises, is molecularly heterogeneous. The next-generation sequencing (NGS)...
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