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ROP39 is an Irgb10-specific parasite effector that modulates acute Toxoplasma gondii virulence

5 Jan 2023

Abstract excerpt

Toxoplasma gondii (T. gondii) is a zoonotic apicomplexan parasite that is an important cause of clinical disability in humans. On a global scale, one third of the human population is infected with T. gondii. Mice and other small rodents are believed to be responsible for transmission of T. gondii to the domestic cat, its definitive host. Interferon-inducible Immunity-Related GTPases (IRG proteins) are important...

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PMID: 36603017
DOI: 10.1371/journal.ppat.1011003

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ROP39 is an Irgb10-specific parasite effector that modulates acute Toxoplasma gondii virulencePMID 36603017Read ↗

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Toxoplasma gondii rhoptry protein38 (TgROP38) affects parasite invasion, egress, and induces IL-18 secretion during early infection.Semantic proximity Read ↗

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