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Toxoplasma gondii rhoptry protein38 (TgROP38) affects parasite invasion, egress, and induces IL-18 secretion during early infection.

Acta biochimica et biophysica Sinica - 1 Aug 2018

Xu Ying, Wang Xiaojia, Liu Jing, Fu Yong, Xu Jianhai, Liu Qun

Abstract excerpt

Toxoplasma rhoptry protein 38 (TgROP38) is a new active kinase that modulates host cell signal transduction and TgROP38 expression shows strain-specificity and stage-specificity in different isolates. In the present study, we overexpressed ROP38 in the RH and prugniaud (PRU) strain (RH+rop38II and PRU+rop38II), disrupted ROP38 (PRUΔROP38) in the PRU strain, complemented the ROP38 (PRUΔROP38comp+) in the PRUΔROP38...

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PMID: 29961856
DOI: 10.1093/abbs/gmy075

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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