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Article

The evolution of the HIV-1 protease folding stability

1 Jul 2022

Abstract excerpt

Abstract The evolution of structural proteins is generally constrained by the folding stability. However, little is known about the particular capacity of viral proteins to accommodate mutations that can potentially affect the protein stability and, in general, the evolution of the protein stability over time. As an illustrative model case, here, we investigated the evolution of the stability of the human...

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PMID: 36601299
DOI: 10.1093/ve/veac115

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