Article
Genetic Consequences of Antiviral Therapy on HIV-1.
Computational and mathematical methods in medicine - 1 Jan 2015
Arenas Miguel
Abstract excerpt
A variety of enzyme inhibitors have been developed in combating HIV-1, however the fast evolutionary rate of this virus commonly leads to the emergence of resistance mutations that finally allows the mutant virus to survive. This review explores the main genetic consequences of HIV-1 molecular evolution during antiviral therapies, including the viral genetic diversity and molecular adaptation. The role of...
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