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Article

Structural and dynamical aspects of HIV-1 protease and its role in drug resistance.

Advances in protein chemistry and structural biology - 1 Jan 2013

Meher Biswa Ranjan, Patel Seema

Abstract excerpt

Acquired immunodeficiency syndrome (AIDS) caused by the retrovirus human immunodeficiency virus (HIV) has become a major epidemic afflicting mankind. The Joint United Nations Program on HIV/AIDS (UNAIDS) projection shows the existence of millions of AIDS patients at the end of 2012. All the Food and Drug Administration (FDA)-approved drugs are getting ineffective due to resistance offered by the mutation-prone...

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PMID: 23954105
DOI: 10.1016/B978-0-12-411636-8.00008-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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