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Article

Evolution of the human immunodeficiency virus type 1 protease: effects on viral replication capacity and protease robustness.

The Journal of general virology - 1 Dec 2012

Capel Elena, Martrus Glòria, Parera Mariona, Clotet Bonaventura, Martínez Miguel Angel

Abstract excerpt

The rapid spread of human immunodeficiency virus type 1 (HIV-1) in humans has been accompanied by continuous extensive genetic diversification of the virus. The aim of this study was to investigate the impact of HIV-1 diversification on HIV-1 replication capacity (RC) and mutational robustness. T...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22933665
DOI: 10.1099/vir.0.045492-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22933665-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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