Article
TCR gene segment usage and HLA alleles that are associated with cancer survival rates also represent racial disparities.
International journal of immunogenetics - 1 Apr 2023
Angelakakis George, Serraneau Karisa S, Barker Vayda R, Callahan Blake M, Tong Wei Lue, Zaman Saif, Huda Taha I, Blanck George
Abstract excerpt
Understanding racial disparities in cancer outcomes continues to be a challenge, with likely many factors at play, including socioeconomic factors and genetic polymorphisms impacting basic cellular and molecular functions. Additionally, it is possible that specific combinations of environment and genetics have specific impacts. T-cell receptor (TCR) gene segment usage, HLA allele combinations have been associated...
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