Article
T cell receptor V-segment frequencies in peripheral blood T cells correlate with human leukocyte antigen type.
The Journal of experimental medicine - 1 Nov 1991
Gulwani-Akolkar B, Posnett D N, Janson C H, Grunewald J, Wigzell H, Akolkar P, Gregersen P K, Silver J
Abstract excerpt
We compared T cell receptor (TCR) V-segment frequencies in human leukocyte antigen (HLA) identical siblings to sibling pairs who differ at one or both HLA haplotypes using four V beta-specific and one V alpha-specific monoclonal antibody. In every one of nine families HLA-identical sibs had the most similar patterns of V-segment frequencies in their peripheral blood, whereas totally mismatched sibs were, in...
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