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Article

Specific HLA alleles, paired with TCR V- and J-gene segment usage, link to distinct multiple myeloma survival rates.

Leukemia & lymphoma - 1 Jul 2021

Huda Taha I, Mihyu Moody, Gozlan Etienne C, Arndt Mary F, Diaz Michael J, Zaman Saif, Chobrutskiy Boris I, Blanck George

Abstract excerpt

Multiple myeloma (MM) immunogenomics studies related to T-cell characterizations and involving large patient sets have been lacking, particularly in comparison to solid tumor types. Thus, we evaluated (i) HLA alleles, and (ii) T-Cell Receptor (TCR) V- and J-gene segment, HLA allele combinations, based on TCR recombinations in blood samples, for their potential associations with overall survival distinctions among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33622167
DOI: 10.1080/10428194.2021.1885655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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