Article
Immunohistochemical Expression of PD-L1 and IDH1 with Detection of MGMT Promoter Methylation in Astrocytoma.
Asian Pacific journal of cancer prevention : APJCP - 1 Dec 2022
Hareedy Amal Ahmed, Rohim El Zahraa Ahmed, Al Sheikh Samar Abdel Monem, Al Shereef Zeinab Abd El Azeem
Abstract excerpt
OBJECTIVE: Programmed death ligand 1 (PD-L1) expression was suggested as a poor prognostic predictor for glioblastoma. While isocitrate dehydrogenase (IDH) has been linked to enhanced overall survival in glioma cells. In glioblastoma patients receiving treatment with alkylating drugs, the methylguanine-DNA methyltransferase (MGMT) promoter's methylation status has been discovered as a potent and distinct...
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