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Article

IDH1 and IDH2 mutations, immunohistochemistry and associations in a series of brain tumors.

Journal of neuro-oncology - 1 Nov 2011

Mellai Marta, Piazzi Angela, Caldera Valentina, Monzeglio Oriana, Cassoni Paola, Valente Guido, Schiffer Davide

Abstract excerpt

A total of 343 brain tumors were studied for IDH1 and IDH2 mutations by direct sequencing and for protein expression by immunohistochemistry with mIDH1(R132H) antibody. Of these, 287 were gliomas (17 pilocytic astrocytomas, 13 grade II and 5 grade III astrocytomas, 167 primary (pGBMs) and 19 secondary (sGBMs) glioblastomas, 36 grade II and 26 grade III oligodendrogliomas and 4 grade II-III oligoastrocytomas). In...

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Share to Brain Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21643842
DOI: 10.1007/s11060-011-0596-3

Genes

IDH1
IDH2
EGFR
MGMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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