Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[IDH1 mutation and MGMT expression in astrocytoma and the relationship with prognosis after radiotherapy].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Oct 2014

Jiang Mengwan, Dong Xianghui, Li Jiayao, Li Jingqi, Qi Jiping

Abstract excerpt

OBJECTIVE: To study the correlation between IDH1 mutation, MGMT expression, clinicopathologic features and post-radiotherapy prognosis in patients with astrocytoma. METHODS: Detection of IDH1 mutation and MGMT expression was carried out in 48 cases of astrocytoma (WHO grade II to III) by EnVision method with immunohistochemical staining. Follow-up data, including treatment response and overall survival time, were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Astrocytoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain Neoplasms

Share to DNA Modification Methylases

Share to DNA Repair Enzymes

Share to Isocitrate Dehydrogenase

Share to Mutant Proteins

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 25567592

Genes

IDH1
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[IDH1 mutation and MGMT expression in astrocytoma and the relationship with prognosis after radiotherapy].PMID 25567592Read ↗

[Correlation between IDH1 mutation and prognosis in supratentorial high-grade astrocytomas].Semantic proximity Read ↗

IDH1 mutations in grade II astrocytomas are associated with unfavorable progression-free survival and prolonged postrecurrence survival.Semantic proximity Read ↗

Immunohistochemical Expression of PD-L1 and IDH1 with Detection of MGMT Promoter Methylation in Astrocytoma.Semantic proximity Read ↗

[Isocitrate dehydrogenase type I mutation as a prognostic factor in glioblastoma and a literature review].Semantic proximity Read ↗

[Relationship between IDH1 mutation and clinic pathologic features in human supratentorial WHO grade II gliomas].Semantic proximity Read ↗

IDH1 mutation and MGMT methylation status predict survival in patients with anaplastic astrocytoma treated with temozolomide-based chemoradiotherapy.Semantic proximity Read ↗

IDH mutations as an early and consistent marker in low-grade astrocytomas WHO grade II and their consecutive secondary high-grade gliomas.Semantic proximity Read ↗

Prognostic value of isocitrate dehydrogenase 1, O6-methylguanine-DNA methyltransferase promoter methylation, and 1p19q co-deletion in Japanese malignant glioma patients.Semantic proximity Read ↗

[Analyses of IDH1 mutation and MGMT promoter methylation status for 5 cases of long-term survivors with glioblastoma].Semantic proximity Read ↗

Integrated analysis of mismatch repair system in malignant astrocytomas.Semantic proximity Read ↗

IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide.Semantic proximity Read ↗

The impact of concurrent temozolomide with adjuvant radiation and IDH mutation status among patients with anaplastic astrocytoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.