Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Improvement of rimocidin production in Streptomyces rimosus M527 by reporter-guided mutation selection.

Journal of industrial microbiology & biotechnology - 13 Feb 2023

Jiang Yujie, Zhang Jinyao, Huang Xinyi, Ma Zheng, Zhang Yongyong, Bechthold Andreas, Yu Xiaoping

Abstract excerpt

In this study, we employed a reporter-guided mutation selection (RGMS) strategy to improve the rimocidin production of Streptomyces rimosus M527, which is based on a single-reporter plasmid pAN and atmospheric and room temperature plasma (ARTP). In plasmid pAN, PrimA, a native promoter of the loading module of rimocidin biosynthesis (RimA) was chosen as a target, and the kanamycin resistance gene (neo) under the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Kanamycin
Share to Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Plasmids

Source

Open in PubMed Open full text

Identifiers

PMID: 36572395
DOI: 10.1093/jimb/kuac030
PMCID: PMC9923380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Improvement of rimocidin production in Streptomyces rimosus M527 by reporter-guided mutation selection.PMID 36572395Read ↗

Sequential improvement of rimocidin production in Streptomyces rimosus M527 by introduction of cumulative drug-resistance mutationsSemantic proximity Read ↗

Daptomycin production enhancement by ARTP mutagenesis and fermentation optimization in Streptomyces roseosporus.Semantic proximity Read ↗

Transposon-based identification of genes involved in the rimocidin biosynthesis in Streptomyces rimosus M527Semantic proximity Read ↗

Development of a CRISPR/Cas9-mediated gene-editing tool in Streptomyces rimosus.Semantic proximity Read ↗

Identification of a gene from Streptomyces rimosus M527 negatively affecting rimocidin biosynthesis and morphological differentiationSemantic proximity Read ↗

Improvement of A21978C production in Streptomyces roseosporus by reporter-guided rpsL mutation selection.Semantic proximity Read ↗

Development and optimization of an intergeneric conjugation system and analysis of promoter activity in Streptomyces rimosus M527Semantic proximity Read ↗

Strain improvement of Streptomyces roseosporus for daptomycin production by rational screening of He-Ne laser and NTG induced mutants and kinetic modeling.Semantic proximity Read ↗

Application of a double-reporter-guided mutant selection method to improve clavulanic acid production in Streptomyces clavuligerus.Semantic proximity Read ↗

Identification of a cluster-situated activator of oxytetracycline biosynthesis and manipulation of its expression for improved oxytetracycline production in Streptomyces rimosus.Semantic proximity Read ↗

[Construction of screening system for mutation of negative regulatory genes in Streptomyces].Semantic proximity Read ↗

Regulation of daptomycin biosynthesis in Streptomyces roseosporus : new insights from genomic analysis and synthetic biology to accelerate lipopeptide discovery and commercial productionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.