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[Construction of screening system for mutation of negative regulatory genes in Streptomyces].

Wei sheng wu xue bao = Acta microbiologica Sinica - 4 Oct 2013

Zhu Yu, Feng Chi, Tan Huarong, Tian Yuqing

Abstract excerpt

OBJECTIVE: We aimed to create a novel report system for screening the mutation of the negative regulatory genes, especially for those repressing the expression of cryptic antibiotics clusters. METHODS: We used marker-free gene disruption strategy, which combines with the "REDIRECT (Rapid Efficien...

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PMID: 24409758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24409758-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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