Article
Telomerase reverse transcriptase promoter mutation and histologic grade in IDH wild-type histological lower-grade gliomas: The value of perfusion-weighted image, diffusion-weighted image, and 18F-FDG-PET.
European journal of radiology - 1 Feb 2023
Ikeda Satoshi, Sakata Akihiko, Fushimi Yasutaka, Okuchi Sachi, Arakawa Yoshiki, Makino Yasuhide, Mineharu Yohei, Nakajima Satoshi, Hinoda Takuya, Yoshida Kazumichi, Miyamoto Susumu, Nakamoto Yuji
Abstract excerpt
PURPOSE: The telomerase reverse transcriptase promoter (TERTp) mutation is an unfavorable prognostic factor in isocitrate dehydrogenase-wildtype (IDHwt) histologically lower-grade astrocytoma (LGA), which was incorporated as a key component in the WHO 2021 classification of IDHwt LGA, replacing histologic grades in the WHO 2016 classification. The purpose of this study was to identify the imaging characteristics...
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