Article
Clinical characteristics and radiological features of glioblastoma, IDH-wildtype, grade 4 with histologically lower-grade gliomas.
Brain tumor pathology - 1 Apr 2023
Motomura Kazuya, Kibe Yuji, Ohka Fumiharu, Aoki Kosuke, Yamaguchi Junya, Saito Ryuta
Abstract excerpt
The 2021 World Health Organization (WHO) classification of central nervous system tumors applied molecular criteria and further integrated histological and molecular diagnosis of gliomas. This classification allows for the diagnosis of isocitrate dehydrogenase wild-type (IDHwt) glioblastoma (GBM), and WHO grade 4 with histologically lower-grade gliomas (LrGGs), even in the absence of high-grade histopathologic...
Topics
- Humans
- Glioblastoma
- Brain Neoplasms
- Glioma
- Prognosis
- Neoplasms, Neuroepithelial
- Isocitrate Dehydrogenase
- Mutation
