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Conventional magnetic resonance imaging-based radiomic signature predicts telomerase reverse transcriptase promoter mutation status in grade II and III gliomas.

Neuroradiology - 1 Jul 2020

Jiang Chendan, Kong Ziren, Zhang Yiwei, Liu Sirui, Liu Zeyu, Chen Wenlin, Liu Penghao, Liu Delin, Wang Yaning, Lyu Yuelei, Zhao Dachun, Wang Yu, You Hui, Feng Feng, Ma Wenbin

Abstract excerpt

PURPOSE: Telomerase reverse transcriptase (TERT) promoter mutation status is an important biomarker for the precision diagnosis and prognosis prediction of lower grade glioma (LGG). This study aimed to construct a radiomic signature to noninvasively predict the TERT promoter status in LGGs. METHODS: Eighty-three local patients with pathology-confirmed LGG were retrospectively included as a training cohort, and 33...

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PMID: 32239241
DOI: 10.1007/s00234-020-02392-1

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