Article
Diffusion and perfusion MRI may predict EGFR amplification and the TERT promoter mutation status of IDH-wildtype lower-grade gliomas.
European radiology - 1 Dec 2020
Park Yae Won, Ahn Sung Soo, Park Chae Jung, Han Kyunghwa, Kim Eui Hyun, Kang Seok-Gu, Chang Jong Hee, Kim Se Hoon, Lee Seung-Koo
Abstract excerpt
OBJECTIVES: Epidermal growth factor receptor (EGFR) amplification and telomerase reverse transcriptase promoter (TERTp) mutation status of isocitrate dehydrogenase-wildtype (IDHwt) lower-grade gliomas (LGGs; grade II/III) are crucial for identifying IDHwt LGG with an aggressive clinical course. The purpose of this study was to assess whether parameters from diffusion tensor imaging, dynamic susceptibility...
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