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Article

The Genetic Diversity and Dysfunctionality of Catalase Associated with a Worse Outcome in Crohn's Disease.

International journal of molecular sciences - 14 Dec 2022

Iborra Marisa, Moret Inés, Busó Enrique, García-Giménez José Luis, Ricart Elena, Gisbert Javier P, Cabré Eduard, Esteve Maria, Márquez-Mosquera Lucía, García-Planella Esther, Guardiola Jordi, Pallardó Federico V, Serena Carolina, Algaba-Chueca Francisco, Domenech Eugeni, Nos Pilar, Beltrán Belén

Abstract excerpt

Chronic gut inflammation in Crohn’s disease (CD) is associated with an increase in oxidative stress and an imbalance of antioxidant enzymes. We have previously shown that catalase (CAT) activity is permanently inhibited by CD. The purpose of the study was to determine whether there is any relationship between the single nucleotide polymorphisms (SNPs) in the CAT enzyme and the potential risk of CD associated with...

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Identifiers

PMID: 36555526
DOI: 10.3390/ijms232415881
PMCID: PMC9785615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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