Article
CAT rs1001179 Single Nucleotide Polymorphism Identifies an Aggressive Clinical Behavior in Chronic Lymphocytic Leukemia.
Hematological oncology - 1 Nov 2024
Galasso Marilisa, Salaorni Vittoria, Moia Riccardo, Mozzo Valentina, Lovato Ester, Cosentino Chiara, Perbellini Omar, Gambino Simona, Lovato Ornella, Carazzolo Maria Elena, Ferrarini Isacco, Quaglia Francesca M, Donadelli Massimo, Romanelli Maria G, Visco Carlo, Krampera Mauro, Gaidano Gianluca, Scupoli Maria T
Abstract excerpt
Chronic lymphocytic leukemia (CLL) is characterized by an extremely variable clinical course. Although several parameters have been shown to be associated with clinical outcomes in patients with CLL, there remains substantial intragroup clinical heterogeneity in otherwise molecularly and staging homogeneous CLL subgroups. We have recently shown that high catalase (CAT) expression identifies patients with an...
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