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Article

Association of Catalase Gene Polymorphisms with Idiopathic Nephrotic Syndrome in a Chinese Pediatric Population.

Laboratory medicine - 5 Jan 2023

Shi Jianrong, Li Wei, Tao Ran, Zhou Dongming, Guo Yajun, Fu Haidong, Sun Anna, Zhang Junfeng, Mao Jianhua

Abstract excerpt

OBJECTIVE: Our aim was to investigate the association between gene polymorphisms in catalase (CAT), a well-known oxidative stress regulator, and susceptibility to idiopathic nephrotic syndrome (INS) or responses to steroid therapy in a Chinese pediatric population. METHODS: We analyzed 3 CAT single-nucleotide polymorphisms (SNVs; rs7943316, rs769217, and rs12270780) using multi-polymerase chain reaction combined...

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PMID: 35964233
DOI: 10.1093/labmed/lmac062

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