Article
Catalase gene C-262T polymorphism: importance in ulcerative colitis.
Journal of gastroenterology and hepatology - 1 May 2013
Khodayari Siamak, Salehi Zivar, Fakhrieh Asl Saba, Aminian Keyvan, Mirzaei Gisomi Nadia, Torabi Dalivandan Saeideh
Abstract excerpt
BACKGROUND AND AIM: Reactive oxygen species (ROS) are by-products of the cellular metabolism and have important roles in the normal physiology of the cell. However, when ROS production exceeds the antioxidant capacity, a state known as oxidative stress, damage to cellular macromolecules emerges. A crucial role in counteracting ROS is played by the enzyme catalase. A common polymorphism in the catalase (CAT)...
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