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Article

The rs1001179 SNP and CpG methylation regulate catalase expression in chronic lymphocytic leukemia.

Cellular and molecular life sciences : CMLS - 16 Sept 2022

Galasso Marilisa, Dalla Pozza Elisa, Chignola Roberto, Gambino Simona, Cavallini Chiara, Quaglia Francesca Maria, Lovato Ornella, Dando Ilaria, Malpeli Giorgio, Krampera Mauro, Donadelli Massimo, Romanelli Maria G, Scupoli Maria T

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is an incurable disease characterized by an extremely variable clinical course. We have recently shown that high catalase (CAT) expression identifies patients with an aggressive clinical course. Elucidating mechanisms regulating CAT expression in CLL is preeminent to understand disease mechanisms and develop strategies for improving its clinical management. In this study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenetics and DNA Methylation

Share to Leukemia, Lymphocytic, Chronic, B-Cell

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 36112236
DOI: 10.1007/s00018-022-04540-7
PMCID: PMC9481481

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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