Article
Are catalase -844A/G polymorphism and activity associated with childhood obesity?
Antioxidants & redox signaling - 1 Dec 2013
Rupérez Azahara I, Olza Josune, Gil-Campos Mercedes, Leis Rosaura, Mesa María D, Tojo Rafael, Cañete Ramón, Gil Angel, Aguilera Concepción M
Abstract excerpt
Catalase (CAT) is a peroxisomal antioxidant enzyme that is up-regulated upon oxidative stress. Previous studies have found associations between some single nucleotide polymorphisms (SNPs) located in the CAT promoter region in a variety of metabolic diseases. This is the first study that analyzes the association between erythrocyte CAT activity and candidate CAT SNPs with childhood obesity. The association study...
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