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Article

Multiplex detection of extensively drug resistant tuberculosis using binary deoxyribozyme sensors.

Biosensors & bioelectronics - 15 Aug 2017

Bengtson Hillary N, Homolka Susanne, Niemann Stefan, Reis Ana Júlia, da Silva Pedro Eduardo, Gerasimova Yulia V, Kolpashchikov Dmitry M, Rohde Kyle H

Abstract excerpt

Current diagnostic tools for Mycobacterium tuberculosis (Mtb) have many disadvantages including low sensitivity, slow turnaround times, or high cost. Accurate, easy to use, and inexpensive point of care molecular diagnostic tests are urgently needed for the analysis of multidrug resistant (MDR) and extensively drug resistant (XDR) Mtb strains that emerge globally as a public health threat. In this study, we...

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Identifiers

PMID: 28284077
DOI: 10.1016/j.bios.2017.02.051
PMCID: PMC5407088

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